Related Experiment Video
Updated: Jul 16, 2026

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound
Published on: December 2, 2014
Aortic elastic properties in patients with coronary artery ectasia
Nurullah Tuzun1, Halil Tanriverdi, Harun Evrengul
1Department of Cardiology, School of Medicine, Suleyman Demirel University, Isparta, Turkey.
Insights
Aortic stiffness is impaired in patients with coronary ectasia (CE) and coronary artery disease (CAD), potentially causing left ventricular (LV) diastolic dysfunction. These aortic elastic parameters strongly predict LV diastolic function.
Area of Science:
- Cardiovascular Medicine
- Medical Imaging
- Biomedical Engineering
Background:
- Coronary ectasia (CE) is a condition affecting coronary arteries.
- Left ventricular (LV) diastolic function is crucial for heart health.
- Understanding aortic elasticity is important for cardiovascular assessment.
Purpose of the Study:
- To investigate aortic elastic characteristics in patients with CE.
- To explore the relationship between aortic elasticity and LV diastolic function.
- To compare CE patients with coronary artery disease (CAD) and healthy controls.
Main Methods:
- Echocardiography was used to assess LV diastolic function.
- Aortic elasticity parameters included aortic strain, beta index, and aortic distensibility.
- Patients were divided into three groups: CE, CAD, and normal coronary arteries.
Main Results:
- LV diastolic function was impaired in both CE and CAD groups compared to controls.
- Aortic elastic parameters were significantly lower in CE and CAD groups.
- Aortic elastic parameters demonstrated strong diagnostic power for LV diastolic function.
Conclusions:
- Aortic stiffness is impaired in patients with CE, similar to CAD patients.
- Increased aortic stiffness may contribute to LV diastolic dysfunction.
- Aortic elastic parameters are valuable indicators of cardiovascular health in CE.
Background:
The purpose of the present study was to investigate the elastic characteristics of the aorta in patients with coronary ectasia (CE) and the relationship between these characteristics and echocardiographic left ventricular (LV) diastolic functions.
Methods And Results:
In the first group there were 35 patients with CE, the second group consisted of 35 patients with coronary artery disease (CAD) and the third group consisted of 35 patients with normal coronary arteries. Echocardiographic investigation was carried out for the assessment of the LV diastolic functions. Aortic strain, beta index and aortic distensibility were used as aortic elasticity parameters. LV diastolic functions were impaired in both the ectasia group and the CAD group as compared with patients with normal coronary arteries. Beta index and aortic distensibility measurements were similar between the CAD and CE groups. The values obtained for aortic strain, beta index and aortic distensibility were lower in the CAD and ectasia groups when compared with the values of the normal group. On performing the stepwise linear multivariable analyses, aortic elastic parameters have been determined to possess the strongest diagnostic power for LV diastolic functions.
Conclusions:
The results of the current study show that stiffness parameters of aorta are impaired in the patients with CE as in the patients with CAD. The increase in aortic stiffness might be responsible for LV diastolic dysfunction.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Elastin is Responsible for Tissue Elasticity
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
Arteries and Arterioles
Aortic Regurgitation III: Medical Management
