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[Hepatitis C in health care professionals: prevalence and association with risk factors]
Luiz Alberto de Souza Ciorlia1, Dirce Maria Trevisan Zanetta
1Serviço de Medicina Ocupacional, Faculdade de Medicina de São José do Rio Preto, Rua Santo Agostinho 281, 15025-220 São José do Rio Preto, SP, Brazil. ciorlampo@yahoo.com.br
Insights
Hepatitis C virus (HCV) infection is more prevalent in healthcare professionals than other groups. Age, job tenure, and blood transfusions are key risk factors for HCV in this population.
Area of Science:
- Epidemiology
- Infectious Diseases
- Occupational Health
Context:
- A university hospital in Southeastern Brazil conducted a study from 1994-1999.
- Included 1,433 healthcare professionals, 872 administrative workers, and 2,583 blood donor candidates.
- Data collected via admission exams, periodic screenings, and post-accident assessments.
Purpose:
- To determine the prevalence of hepatitis C virus (HCV) infection among healthcare professionals.
- To identify occupational and non-occupational risk factors associated with HCV infection in this group.
Summary:
- HCV prevalence was significantly higher in healthcare professionals (1.7%) compared to administrative workers (0.5%) and blood donor candidates (0.2%).
- Logistic regression revealed a 50% increased risk for every five years of age.
- Significant associations found between longer job tenure, blood transfusion history, and positive HCV serology among healthcare workers.
Impact:
- Highlights increased risk of HCV infection in healthcare settings.
- Informs targeted prevention strategies for healthcare professionals.
- Emphasizes the importance of age, occupational exposure, and transfusion history in HCV risk assessment.
Objective:
To evaluate the prevalence and risk factors for hepatitis C virus infection among health care professionals.
Methods:
The study was carried out at a university hospital in the municipality of São José do Rio Preto, Southeastern Brazil, between January 1994 and December 1999. There were included 1,433 health care professionals, 872 administrative workers, and 2,583 blood donor candidates. Data were collected during admission examinations, periodic screenings, and after occupational accidents. Occupational and non-occupational information was obtained by means of a questionnaire. Data were analyzed using Chi-square and Kruskal-Wallis tests and logistic regression analysis.
Results:
Prevalence of hepatitis C infection among health care professionals (1.7%) was significantly higher than among administrative workers (0.5%; p=0.007) and blood donor candidates (0.2%; p=0.001). Regarding occupational factors, time in the job was significantly longer (p=0.016) among health care professionals with positive serology than among those with negative serology. Multiple regression analysis showed a 50% increase in risk for every five years of age. There was a significant association between blood transfusion and positive serology among health care workers.
Conclusions:
Health care professionals show greater prevalence of hepatitis C than administrative workers and blood donation candidates. Among those with positive serology, occupational and non-occupational factors of greatest risk were age, time in the job, and blood transfusion.
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