[Hepatitis C in health care professionals: prevalence and association with risk factors]

Luiz Alberto de Souza Ciorlia1, Dirce Maria Trevisan Zanetta

  • 1Serviço de Medicina Ocupacional, Faculdade de Medicina de São José do Rio Preto, Rua Santo Agostinho 281, 15025-220 São José do Rio Preto, SP, Brazil. ciorlampo@yahoo.com.br

Insights

Hepatitis C virus (HCV) infection is more prevalent in healthcare professionals than other groups. Age, job tenure, and blood transfusions are key risk factors for HCV in this population.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Occupational Health

Context:

  • A university hospital in Southeastern Brazil conducted a study from 1994-1999.
  • Included 1,433 healthcare professionals, 872 administrative workers, and 2,583 blood donor candidates.
  • Data collected via admission exams, periodic screenings, and post-accident assessments.

Purpose:

  • To determine the prevalence of hepatitis C virus (HCV) infection among healthcare professionals.
  • To identify occupational and non-occupational risk factors associated with HCV infection in this group.

Summary:

  • HCV prevalence was significantly higher in healthcare professionals (1.7%) compared to administrative workers (0.5%) and blood donor candidates (0.2%).
  • Logistic regression revealed a 50% increased risk for every five years of age.
  • Significant associations found between longer job tenure, blood transfusion history, and positive HCV serology among healthcare workers.

Impact:

  • Highlights increased risk of HCV infection in healthcare settings.
  • Informs targeted prevention strategies for healthcare professionals.
  • Emphasizes the importance of age, occupational exposure, and transfusion history in HCV risk assessment.
Abstract

Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Standard Precaution01:26

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...