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Published on: February 25, 2020
Prosthetic devices: challenges and implications of robotic implants and biological interfaces
J C K Lai1, M P Schoen, A Perez Gracia
1Department of Pharmaceutical Sciences, College of Pharmacy, 921 S. 8th Avenue, Stop 8288, Pocatello, ID, 83209-8288, USA. lai@otc.isu.edu
Summary
Developing ideal prosthetic implants requires addressing challenges in biomimicry, control, and biocompatibility. Understanding tissue reactions and inflammatory responses is crucial for functional and comfortable robotic prosthetics.
Area of Science:
- Biomedical Engineering
- Biomaterials Science
- Prosthetics Research
Background:
- Current robotic prosthetic implants face challenges in meeting user needs for control, comfort, and aesthetics.
- Existing literature on prosthetics and robotic implants is extensive, necessitating a focused review.
Purpose of the Study:
- To identify key challenges and opportunities in prosthetic implant design.
- To review advancements and issues in biomimetic artificial hands and prosthetic control using electromyography (EMG) signals.
- To examine tissue reactions to implant materials and the impact of inflammation on sensor signal transmission.
Main Methods:
- Literature review focusing on four key areas: biomimetic artificial hands, EMG-based prosthetic control, implant material biocompatibility, and inflammatory responses affecting sensor function.
- Analysis of biological interfaces between implants and surrounding tissues.
Main Results:
- Challenges persist in achieving ideal prosthetic functionality, including ease of control, comfort, and cosmetic appeal.
- Tissue reactions and inflammatory responses at the biological interface significantly impact the performance and longevity of implanted sensors.
- Understanding pathophysiological changes at biological interfaces is vital for improving prosthetic biocompatibility.
Conclusions:
- Interdisciplinary collaboration among biomedical engineers, tissue engineers, biomaterial scientists, and biomedical scientists is essential for holistic and synergistic prosthetic design.
- Future prosthetic designs must prioritize biocompatibility and address the complexities of biological interfaces to meet user 'ideals'.

