Related Experiment Video
Updated: Jul 16, 2026
Quantitative Immunohistochemistry of the Cellular Microenvironment in Patient Glioblastoma Resections
Published on: July 31, 2017
[The features of pathology and immunohistochemistry in orbital meningiomas]
Yan Hei1, Xin-wu Zhang, Yi Wang
1Institute of Orbital Disease, Armed Police General Hospital, Beijing 100039, China. heiyan842@yahoo.com.cn
Objective:
To study the biological characteristics of orbital meningiomas using histological and immunohistochemistrical analysis.
Methods:
19 specimens taking from orbital meningiomas were included in the study. HE staining was used for histology analysis and the immunohistochemistry was applied to demonstrate the expression of Vimentin, EMA, Ki-67, p53 in the tissue of orbital meningiomas.
Results:
The main configuration of orbital meningiomas was meningothelial, transitional and fibrous meningioma. The expression rations of Vimentin and EMA were 94.75% (18/19), 52.63% (10/19), respectively. The detected rations of Ki-67 and p53 were very lower.
Conclusions:
Our study shows that the major histological configuration of orbital meningiomas are meningothelial, transitional and fibrous meningioma. Compare with intracranial meningiomas, the expression rate of EMA in orbital meningiomas is lower. No difference of the expression rates of p53 and Ki-67 are found in benignant, recrudescent and malignant of tumor.
