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[Exercise capacity evaluation after percutaneous balloon pulmonary valvuloplasty in children with pulmonary valve
Ying Guo1, Ai-qing Zhou, Kun Sun
1Cardiovascular Department, Shanghai Children's Medical Center, Shanghai Jiaotong University, Shanghai 200127, China. guoyingscmc@163.com
Insights
Children undergoing percutaneous balloon pulmonary valvuloplasty (PBPV) for pulmonary valve stenosis show exercise capacity comparable to healthy peers. This minimally invasive procedure effectively restores normal exercise function in pediatric patients.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Cardiovascular Physiology
Context:
- Isolated pulmonary valve stenosis is a congenital heart defect affecting the valve between the right ventricle and pulmonary artery.
- Percutaneous balloon pulmonary valvuloplasty (PBPV) is a minimally invasive procedure to treat pulmonary valve stenosis.
- Assessing long-term functional outcomes, specifically exercise capacity, is crucial for pediatric cardiac interventions.
Purpose:
- To evaluate the exercise capacity of children after PBPV for isolated pulmonary valve stenosis.
- To compare the exercise performance of these children with a healthy control group.
- To identify factors influencing exercise capacity post-PBPV.
Summary:
- 46 children with isolated pulmonary valve stenosis underwent PBPV and subsequent treadmill exercise testing.
- Post-PBPV, children demonstrated a mean work capacity approximately 90% of healthy controls.
- Heart rate and blood pressure responses to exercise were comparable to healthy children, with no significant ECG abnormalities noted.
Impact:
- PBPV is an effective treatment for isolated pulmonary valve stenosis, restoring near-normal exercise capacity in pediatric patients.
- Findings support PBPV as a viable therapeutic option, improving quality of life and functional outcomes.
- Age at operation and balloon-to-valve diameter ratio are potential predictors of exercise capacity post-PBPV.
Objective:
To assess exercise capacity after percutaneous balloon pulmonary valvuloplasty (PBPV) in children with isolated pulmonary valve stenosis.
Methods:
Treadmill exercise testing was performed in 46 children (6.3 +/- 3.1 years, ranging 1 to 12.5 years) with isolated pulmonary valve stenosis post PBPV and in 294 healthy children. Exercise capacity, change in heart rate, blood pressure, and electrocardiogram during exercise were observed.
Results:
Post PBPV, the transvalvular gradient was below 25 mm Hg (1 mm Hg = 0.133 kPa) in all patients. The mean work capacity in post PBPV children was about 90 percent of that in healthy children. Heart rate and blood pressure response to exercise is comparable to healthy children. Factors associated with exercise capacity include age at operation and the ratio of balloon/pulmonary valve diameter. Exercise-induced uniform ventricular premature contraction in 5 children post PBPV and no ST segment change was observed.
Conclusion:
Exercise capacity post percutaneous balloon pulmonary valvuloplasty in children with isolated pulmonary valve stenosis was comparable to that in healthy children.
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