Jove
Visualize
Contact Us

Related Experiment Video

Updated: Jul 16, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Microfluidic chip accomplishing self-fluid replacement using only capillary force and its bioanalytical application.

Kwang Hyo Chung1, Jung Woo Hong, Dae-Sik Lee

  • 1Biosensor Team, ETRI, Daejeon 305-350, Republic of Korea.

Analytica Chimica Acta
|March 28, 2007
PubMed
Summary

This study presents a polymer microfluidic chip for automated bioanalysis using only capillary flow. The chip enables controlled fluid replacement, simplifying complex lab-on-a-chip applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced breath analysis through hierarchical deep convolutional neural network for multi-cancer screening.

NPJ digital medicine·2026
Same author

Field-deployable modular absorbance analysis platform with standardized electronics for point-of-care diagnostics.

Biosensors & bioelectronics·2025
Same author

Non-spectroscopic multiplex molecular diagnosis for simultaneous detection of virulence and antibiotic resistance genes from pathogenic bacteria.

Biosensors & bioelectronics·2025
Same author

Superhydrophilic Silica-Coated Au Nanoislands for Efficient Capture and Enhanced SERS Detection of Airborne Biomarkers.

ACS applied materials & interfaces·2025
Same author

Shh agonist enhances maturation in homotypic Lgr5-positive inner ear organoids.

Theranostics·2025
Same author

Multigas Identification by Temperature-Modulated Operation of a Single Anodic Aluminum Oxide Gas Sensor Platform and Deep Learning Algorithm.

ACS sensors·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Biomedical Engineering
  • Microfluidics
  • Analytical Chemistry

Background:

  • Automated fluid handling is crucial for lab-on-a-chip devices.
  • External controls often complicate microfluidic systems.
  • Efficient fluid replacement is necessary for multi-step bioassays.

Purpose of the Study:

  • To develop a polymer microfluidic chip for automated sample flow and replacement.
  • To demonstrate fluidic control solely through natural capillary flow.
  • To validate the chip's performance in a bioanalytical reaction.

Main Methods:

  • Designing microchannel and chamber geometry using theoretical analysis and numerical simulations.
  • Fabricating the microfluidic chip using polymer replication techniques.

More Related Videos

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
14:53

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Related Experiment Videos

Last Updated: Jul 16, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
14:53

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

  • Testing the chip with an enzyme (HRP)-catalyzed precipitation reaction.

    • Main Results:

    • Automated sample flow and replacement were achieved without external controls.
    • Capillary flow was successfully managed through precise geometric design.
    • The chip demonstrated good performance in a biochemical analysis application.

    Conclusions:

    • The developed polymer microfluidic chip enables autonomous fluid operations.
    • This technology is suitable for cost-effective and rapid fabrication.
    • The method is applicable to various lab-on-a-chip systems requiring fluid exchange.