Distribution of HIV type 1 infection in childbearing women in California

F J Capell1, D J Vugia, V L Mordaunt

  • 1California Department of Health Services.

Insights

Human immunodeficiency virus (HIV) infection affects 7.4 per 10,000 childbearing women in California. Prevalence is highest among Black, Hispanic, and San Francisco Bay Area women, indicating a growing concern for Hispanic women and acquired immunodeficiency syndrome (AIDS) cases.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • Rising incidence of acquired immunodeficiency syndrome (AIDS) among heterosexuals and children in California.
  • Need to assess the prevalence of human immunodeficiency virus (HIV)-1 infection in childbearing women.

Purpose of the Study:

  • To determine the period prevalence of HIV-1 infection among childbearing women in California using a newborn serosurvey.
  • To identify demographic groups with higher HIV-1 prevalence.

Main Methods:

  • Blinded serosurvey of newborns from 99% of California births in Q3 1988 (n=135,808).
  • Dried blood specimens tested for HIV-1 antibody using enzyme immunoassay and confirmed by Western blot.
  • Data linked only to maternal demographic categories.

Main Results:

  • Period prevalence of HIV-1 infection was 7.4 per 10,000 childbearing women.
  • Prevalence was highest among Black women.
  • Elevated prevalence observed in Hispanic and San Francisco Bay Area women.

Conclusions:

  • HIV-1 infection is a significant concern among California childbearing women.
  • Specific demographic groups, including Black and Hispanic women, are disproportionately affected.
  • Hispanic women are projected to represent an increasing proportion of future AIDS cases.

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