Apical hypertrophic cardiomyopathy: potential utility of Strain imaging

Madhulatha Reddy1, Deepak Thatai, Juan Bernal

  • 1Division of Cardiology, Wayne State University, Harper University Hospital, Detroit Medical Center, Detroit MI 48201, USA.

Insights

Diagnosing apical hypertrophic cardiomyopathy (HCM) can be challenging. Two-dimensional (2D) strain imaging revealed paradoxical systolic lengthening in the apex, aiding diagnosis in two patients.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Hypertrophic cardiomyopathy (HCM) is commonly diagnosed via echocardiography.
  • The apical variant of HCM, also known as the 'Japanese variant,' is rare and diagnostically challenging.
  • Novel imaging techniques like strain imaging are increasing interest in HCM diagnosis.

Purpose of the Study:

  • To investigate the utility of 2D strain imaging in diagnosing apical HCM.
  • To describe a novel finding of paradoxical apical strain in apical HCM patients.

Main Methods:

  • Utilized two-dimensional (2D) strain echocardiography.
  • Analyzed tissue velocities through frame-to-frame tracking of acoustic markers.
  • Assessed strain parameters, comparing them to tissue-Doppler-derived strain.

Main Results:

  • Observed paradoxical apical strain (systolic lengthening) in two patients with apical HCM.
  • This finding was present without overt apical dyskinesis on conventional imaging.
  • 2D strain imaging provided a novel diagnostic marker.

Conclusions:

  • Two-dimensional strain imaging offers a valuable tool for diagnosing apical HCM.
  • Paradoxical apical strain is a potential indicator for this rare HCM variant.
  • This technique can facilitate earlier and more accurate diagnosis of apical HCM.