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Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
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Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

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Cholesterol-sensitive modulation of transcytosis

Julieta Leyt1, Naomi Melamed-Book, Jean-Pierre Vaerman

  • 1Department of Cell and Animal Biology, Institute of Life Sciences, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel.

Molecular Biology of the Cell
|March 30, 2007
PubMed
Summary

Cholesterol-rich lipid rafts are crucial for polarized sorting in cells. Disrupting these domains affects endosomal traffic and stimulates transcytosis, revealing a compensatory mechanism for cell cholesterol balance.

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