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Streptococcus associated toxic shock.

C Torres-Martínez1, D Mehta, A Butt

  • 1Academic Department of Paediatrics, St Mary's Hospital Medical School, London.

Archives of Disease in Childhood
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Group A beta-haemolytic streptococcus (GABHS) can cause a severe toxic shock-like syndrome in children. Early recognition and aggressive treatment are crucial for managing this serious condition.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Group A beta-haemolytic streptococcus (GABHS) infections have shown a changing spectrum of disease.
  • Toxic shock-like syndrome has been recently described in adults caused by GABHS.

Observation:

  • Four children presented with acute illness characterized by rapid shock, rash, and multisystem organ involvement.
  • Three children had extensive cutaneous/soft tissue infections; one had peritonitis.
  • All four children developed bacteremia and fulfilled diagnostic criteria for toxic shock syndrome.

Findings:

  • The children experienced severe complications including electrolyte imbalances and desquamation.
  • Treatment involved aggressive cardiovascular resuscitation and antibiotics.

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  • All patients survived but required prolonged hospitalization and treatment for complications.

    • Implications:

    • Streptococcal toxic shock syndrome (STSS) is a distinct clinical entity in previously healthy children.
    • This syndrome necessitates prompt diagnosis and intensive management.
    • Understanding STSS is vital for pediatric infectious disease specialists and critical care providers.