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Updated: Jul 16, 2026

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection
Published on: May 24, 2020
New insights into the subversion of the chemokine system by poxviruses
1Centro de Biología Molecular Severo Ochoa, Campus Universidad Autónoma, Cantoblanco, Madrid, Spain. aalcami@cbm.uam.es
Abstract:
Viruses encode immune evasion mechanisms to survive in the immunocompetent host. Chemokines mediate the migration of immune cells and their critical role in immunity is emphasized by the numerous virus-encoded strategies to modulate their activity. Evidence published in this issue of the European Journal of Immunology uncovers novel mechanisms encoded by vaccinia virus to inhibit the chemokine-mediated migration of DC, an important event in the initiation of the immune response to viral infections.
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