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Corticosteroids and beta2 agonists differentially regulate rhinovirus-induced interleukin-6 via distinct Cis-acting

Michael R Edwards1, Jennifer Haas, Rey A Panettieri

  • 1Department of Respiratory Medicine, National Heart and Lung Institute and Wright Fleming Institute of Infection and Immunity, Imperial College London, London W2 1PG, United Kingdom. michael.edwards@ic.ac.uk

The Journal of Biological Chemistry
|March 31, 2007
PubMed
Summary

Beta(2) agonists like salmeterol and salbutamol increase interleukin-6 (IL-6) production during viral infections, while fluticasone propionate reduces it. This highlights complex interactions between asthma medications and airway inflammation.

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