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Related Experiment Video

Updated: Jul 16, 2026

Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
11:03

Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Published on: January 22, 2018

Atypical myopic retinoschisis.

M Rosa Sanabria1, Rosa M Coco

  • 1Hospital Rio Hortega, Spain.

Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
|April 3, 2007
PubMed
Summary

A 34-year-old woman experienced vision loss due to a rare form of retinal schisis, complicated by hemorrhage and myopia. This case highlights atypical schisis progression possibly driven by vitreous traction.

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Myopia Research

Background:

  • High myopia (-11 diopters) presents unique challenges in retinal health.
  • Retinoschisis, a splitting of the retinal layers, is typically peripheral and asymptomatic.
  • Juxtafoveal hemorrhage can cause significant visual disturbances.

Observation:

  • A 34-year-old myopic woman presented with central vision loss (scotoma) and visual distortion (metamorphopsia) in her right eye.
  • Diagnostic imaging, including fluorescein angiography and optical coherence tomography (OCT), was performed.
  • OCT revealed retinal splitting in the juxtafoveal and peripapillary regions, with no peripheral abnormalities.

Findings:

  • The patient's condition involved a juxtafoveal hemorrhage and symptomatic retinal splitting.

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Published on: April 3, 2016

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  • Choroidal neovascularization and lacquer cracks were excluded by fluorescein angiography.
  • This case represents an atypical presentation of myopic schisis, characterized by symptoms, hemorrhage, and macular involvement.

    • Implications:

    • This atypical schisis may represent an extension of subclinical peripheral schisis into the macula.
    • Vitreous tractional forces could be a contributing factor to the progression and symptomatic nature of the schisis.
    • Understanding these atypical presentations is crucial for managing high myopia complications.