Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peptide based malaria vaccine development: personal considerations.

Giampietro Corradin1

  • 1Biochemistry Department, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland. giampietro.corradin@unil.ch

Microbes and Infection
|April 3, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cross-reactivity of rPvs48/45, a recombinant Plasmodium vivax protein, with plasma from Plasmodium falciparum endemic areas of Africa.

PloS one·2025
Same author

Cross-reactivity of r<i>Pvs</i>48/45, a recombinant <i>Plasmodium vivax</i> protein, with sera from <i>Plasmodium falciparum</i> endemic areas of Africa.

bioRxiv : the preprint server for biology·2024
Same author

A SARS-CoV-2 Spike Receptor Binding Motif Peptide Induces Anti-Spike Antibodies in Mice andIs Recognized by COVID-19 Patients.

Frontiers in immunology·2022
Same author

Seroreactivity of the Severe Acute Respiratory Syndrome Coronavirus 2 Recombinant S Protein, Receptor-Binding Domain, and Its Receptor-Binding Motif in COVID-19 Patients and Their Cross-Reactivity With Pre-COVID-19 Samples From Malaria-Endemic Areas.

Frontiers in immunology·2022
Same author

Randomized clinical trial to assess the protective efficacy of a Plasmodium vivax CS synthetic vaccine.

Nature communications·2022
Same author

Immunogenicity of full-length P. vivax rPvs48/45 protein formulations in BALB/c mice.

Vaccine·2021
Same journal

The extent of monocytic myeloid suppressor cells induction determines the host immune response during Mycobacterium avium infection.

Microbes and infection·2025
Same journal

Culture-attenuated pathogenic Leptospira lose the ability to survive complement lytic activity due to decreased C4BP uptake.

Microbes and infection·2025
Same journal

Exploring the link between genetically predicted plasma cathepsins and COVID-19: A mendelian randomization study of susceptibility and severity.

Microbes and infection·2025
Same journal

Laboratory parameters and serum tube agglutination test as markers for brucellosis treatment response.

Microbes and infection·2025
Same journal

Corrigendum to "Lactococcus lactis and Bifidobacterium longum attenuate Clostridioides difficile- or Clostridium symbiosum-induced colitis and depression/anxiety-like behavior in male mice" [Microb Infect 27(7) (2025) 105560].

Microbes and infection·2025
Same journal

Disrupted Microbiome-Metabolome networks underlie gut barrier and immune imbalance in severe fever with thrombocytopenia syndrome.

Microbes and infection·2025
See all related articles

Synthetic peptide vaccines offer a promising avenue for malaria vaccine development, leveraging genomic data for rapid antigen discovery. Global collaboration is essential to overcome malaria challenges.

Area of Science:

  • Vaccinology
  • Parasitology
  • Genomics

Background:

  • Malaria remains a significant global health burden, necessitating innovative vaccine strategies.
  • The synthetic peptide approach has emerged as a key methodology in vaccine research.
  • Recent advancements have accelerated progress in malaria vaccine discovery.

Purpose of the Study:

  • To provide a historical overview of synthetic peptide approaches in malaria vaccine development.
  • To highlight recent accomplishments and applications in high-throughput antigen discovery.
  • To emphasize the importance of global cooperation in malaria eradication efforts.

Main Methods:

  • Review of historical data on synthetic peptide vaccine development for malaria.
  • Description of high-throughput antigen discovery methods utilizing genomic information.

Related Experiment Videos

  • Discussion of collaborative strategies for global malaria control.

    • Main Results:

    • The synthetic peptide approach has a documented history in malaria vaccine research.
    • Genomic information enables efficient high-throughput identification of potential malaria antigens.
    • Recent accomplishments demonstrate the viability of this approach.

    Conclusions:

    • The synthetic peptide approach is a valuable tool for malaria vaccine discovery and development.
    • High-throughput antigen discovery, informed by genomics, accelerates progress.
    • A unified global effort is critical for the ultimate defeat of malaria.