Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Insufficient Sleep and Sleep Deprivation

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A maternal exon H splice-site variant leading to pseudohypoparathyroidism type 1B with broad methylation defects in GNAS-differentially methylated regions.

Clinical epigenetics·2026

Same author

A comprehensive long-read sequencing system to assess DNA methylation at differentially methylated regions and imprinting-disorder-related genes.

Genome medicine·2025

Same author

Maternal Microchimerism Is Uncommon in Patients with Hypospadias.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation·2025

Same author

<i>KCNJ11</i> readthrough variant in a patient with congenital hyperinsulinism.

Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology·2025

Same author

DHX37 variants in patients with 46,XY disorders or differences of sex development.

Human genome variation·2025

Same author

Multifocal Genomic Reconstruction Leading to Germline Structural Variants.

Methods in molecular biology (Clifton, N.J.)·2025

Search research articles

Related Experiment Video

Updated: Jul 15, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

Vitamin A deficiency induces a decrease in EEG delta power during sleep in mice.

Kazuyoshi Kitaoka¹, Atsushi Hattori, Sachiko Chikahisa

¹Department of Integrative Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan.

|April 3, 2007

Summary

Vitamin A deficiency in mice reduced sleep EEG delta power and spontaneous activity. Sleep deprivation temporarily restored delta power, suggesting a link to dopamine function.

More Related Videos

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

Establishing a Device for Sleep Deprivation in Mice

Establishing a Device for Sleep Deprivation in Mice

Published on: September 22, 2023

Related Experiment Videos

Last Updated: Jul 15, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

Establishing a Device for Sleep Deprivation in Mice

Establishing a Device for Sleep Deprivation in Mice

Published on: September 22, 2023

Area of Science:

Neuroscience
Nutritional Science

Background:

Vitamin A (retinol) derivatives are implicated in sleep electroencephalogram (EEG) delta oscillations.
Previous findings require independent confirmation and further investigation into the underlying mechanisms.

Purpose of the Study:

To investigate the role of vitamin A in sleep EEG delta oscillations and behavior.
To examine the impact of vitamin A deficiency on striatal monoamines.

Main Methods:

Mice were fed a vitamin A-deficient (VAD) diet for 4 weeks.
Sleep EEG, behavior, and striatal monoamines were recorded and quantified.
Sleep deprivation was used to assess delta power recovery.

Main Results:

VAD mice showed significantly decreased delta power in non-rapid eye movement (NREM) sleep EEG.
Spontaneous activity was reduced in VAD mice over a 24-hour period.
Dihydroxyphenylacetic acid, a dopamine metabolite, was significantly decreased in VAD mice striatum.

Conclusions:

Vitamin A deficiency attenuates NREM sleep delta power and reduces spontaneous activity.
These effects may be associated with altered dopaminergic function in the striatum.