Jove
Visualize
Contact Us

Related Experiment Videos

Systems biology--an engineering perspective.

A Kremling1, J Saez-Rodriguez

  • 1Systems Biology Group, Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany. kremling@mpi-magdeburg.mpg.de

Journal of Biotechnology
|April 3, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets.

Nature communications·2022
Same author

Type and capacity of glucose transport influences succinate yield in two-stage cultivations.

Microbial cell factories·2018
Same author

Application of theoretical methods to increase succinate production in engineered strains.

Bioprocess and biosystems engineering·2017
Same author

Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.

Oncogene·2016
Same author

Interplay of the PtsN (EIIA(Ntr)) protein of Pseudomonas putida with its target sensor kinase KdpD.

Environmental microbiology reports·2015
Same author

Modeling the Interplay of Pseudomonas putida EIIA with the Potassium Transporter KdpFABC.

Journal of molecular microbiology and biotechnology·2015
Same journal

High-level De novo Biosynthesis of Plant-Derived Pinosylvin in Yarrowia lipolytica via Metabolic Engineering and Surfactant-Mediated Fermentation.

Journal of biotechnology·2026
Same journal

The effect of reduced graphene oxide in chitosan-based nanoparticles on the enzymatic properties of the immobilized enzyme.

Journal of biotechnology·2026
Same journal

High-level biosynthesis of gastrodin in engineered Escherichia coli.

Journal of biotechnology·2026
Same journal

From plasmid sequence to process design: A computational analysis of metabolism in the context of plasmid DNA manufacturing.

Journal of biotechnology·2026
Same journal

Development of an inducible cellobiohydrolase promoter and its application for enhancing the production of ganoderic acids in Ganoderma lingzhi.

Journal of biotechnology·2026
Same journal

Malic acid and allied exogenous chemicals induces desaturase gene expression and elevates PUFA production in marine microalgae Isochrysis sp.

Journal of biotechnology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Systems biology integrates engineering, particularly chemical engineering, for experimental and theoretical advancements. This review highlights novel modeling and analysis techniques for biochemical systems.

Area of Science:

  • Systems biology
  • Chemical engineering
  • Biochemical systems analysis

Background:

  • Systems biology has rapidly advanced through interdisciplinary contributions.
  • Engineering science, especially chemical engineering, has significantly impacted systems biology's development.
  • Both experimental and theoretical aspects of systems biology have benefited from external disciplines.

Purpose of the Study:

  • To review and illustrate the contributions of chemical engineering to systems biology.
  • To focus on potentially useful, yet underexplored, techniques for biochemical systems analysis.
  • To bridge the gap between engineering methodologies and biological system understanding.

Main Methods:

  • Literature review of chemical engineering contributions to systems biology.

Related Experiment Videos

  • Analysis of modeling approaches used in systems biology.
  • Exploration of advanced model analysis techniques.
  • Focus on underutilized methods for biochemical system analysis.

    • Main Results:

    • Chemical engineering provides essential modeling and analysis tools for systems biology.
    • Several under-exploited techniques offer significant potential for analyzing complex biochemical systems.
    • Integration of engineering principles enhances the understanding of biological complexity.

    Conclusions:

    • Chemical engineering is a vital discipline for the advancement of systems biology.
    • Novel engineering techniques can unlock deeper insights into biochemical systems.
    • Further exploration of these techniques is recommended for future systems biology research.