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Murine Model of Allergen Induced Asthma
08:05

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Published on: May 14, 2012

Diagnostic tests for asthma in firefighters.

David Miedinger1, Prashant N Chhajed, Michael Tamm

  • 1Clinic for Pneumology, University Hospital, Basel, Switzerland. miedingerd@uhbs.ch

Chest
|April 3, 2007
PubMed
Summary

Asthma is significantly underdiagnosed in firefighters. A combination of symptom questionnaires and bronchial challenge tests can effectively identify asthma in this profession.

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Area of Science:

  • Occupational Medicine
  • Pulmonology
  • Diagnostic Medicine

Background:

  • Firefighting requires stringent medical standards, often excluding individuals with asthma.
  • Underdiagnosis of asthma in firefighters poses a risk to both the individual and public safety.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of various tests for asthma in a firefighter cohort.
  • To determine the prevalence of underdiagnosed asthma among firefighters.

Main Methods:

  • Prospective study of 101 firefighters using questionnaires, spirometry, airway challenge tests (direct and indirect), exhaled nitric oxide, and skin-prick tests.
  • Asthma definition: combination of respiratory symptoms and airway hyperresponsiveness.

Main Results:

  • Physician-diagnosed asthma was confirmed in only 4% of firefighters, while the study identified asthma in 14%.
  • Wheezing showed high sensitivity (78%) and specificity (93%) for asthma diagnosis.
  • Bronchial airway challenge with mannitol demonstrated the highest sensitivity (92%) and specificity (97%) for diagnosing asthma.

Conclusions:

  • Asthma is considerably underdiagnosed in the firefighter population.
  • Integrating symptom questionnaires with bronchial challenge tests is recommended for routine asthma assessment in active firefighters and candidates.