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Updated: Jul 15, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Functional outcome after severe cerebral venous thrombosis
Andreas Bender1, Gernot Schulte-Altedorneburg, Thomas E Mayer
1Department of Neurology, University of Munich Klinikum Grosshadern, Marchioninistr 15, 81377 Munich, Germany. andreas.bender@med.uni-muenchen.de
Severe cerebral venous thrombosis (CVT) can be fatal, but survivors often achieve good functional outcomes and quality of life (QOL). This suggests intensive care is warranted for severe CVT cases.
Area of Science:
- Neurology
- Critical Care Medicine
- Vascular Neurology
Background:
- Severe cerebral venous thrombosis (CVT) is a rare but potentially fatal cerebrovascular condition.
- While uncomplicated CVT often has good outcomes, severe cases require intensive care.
Purpose of the Study:
- To evaluate long-term functional outcomes and quality of life (QOL) in patients with severe CVT.
- To assess the impact of intensive care treatment on severe CVT prognosis.
Main Methods:
- Retrospective analysis of 10 patients admitted to a neurological ICU with severe CVT.
- Utilized the modified Rankin Scale, SF-36, and Psychological General Well-Being index for outcome assessment.
Main Results:
- The mortality rate for severe CVT in this cohort was 50%.
- Among survivors, 4 out of 5 demonstrated good functional outcomes and normal QOL.
- These positive outcomes were observed despite a very severe clinical course during the acute phase.
Conclusions:
- Extensive life-sustaining therapy may be justified in severe CVT cases.
- Survival of the acute phase in severe CVT can lead to favorable long-term functional and QOL outcomes.
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