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[Spontaneous cleft palate in CF#1/Ohu mice]
Y Matsushima1, M Ohne, T Irino
1Department of Laboratory Animal Science, Ohu University, School of Dentistry, Fukushima, Japan.
Jikken Dobutsu. Experimental Animals
|January 1, 1992
Abstract:
We found a spontaneous cleft palate in a mouse of CF#1/Ohu (Ohu University, Japan). Further, the frequency of the spontaneous cleft palate in strains of CF#1/Jms (Institute of Medical Science, University of Tokyo, Japan) and CF#1/Jah (National Institute of Animal Health, Japan) were about 3%, respectively. The frequency and the types of spontaneous cleft palate in CF#1 were clearly different from those in A/J and CL/Fr strains which were used as model animals of lip and cleft palate. We think that CF#1 is the new animal models to analyze a cleft palate genetically and biochemically.