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[New furoquinolins from Monnieria trifolia]
C Moulis1, J Gleye, I Fourasté
1Laboratoire de Matière Médicale, Faculté des Sciences Pharmaceutiques, Université Toulouse III, France.
Planta Medica
|August 1, 1981
Summary
Four new furoquinoline alkaloids were discovered in Monnieria trifolia leaves. Their chemical structures were identified using advanced spectrometric techniques and chemical analysis.
Area of Science:
- Phytochemistry: Focuses on the isolation and structural elucidation of plant-derived compounds.
Context:
- Monnieria trifolia is a plant species known for its potential bioactive constituents.
- Furoquinoline alkaloids represent a class of natural products with diverse pharmacological activities.
Purpose:
- To isolate and characterize novel furoquinoline alkaloids from the leaves of Monnieria trifolia.
- To elucidate the chemical structures of these newly identified compounds using spectroscopic data.
Summary:
- Four new furoquinoline alkaloids, named evolatine, evoxine, 6-methoxy-7-hydroxy-dictamnine, and haplopine, were successfully isolated from Monnieria trifolia leaves.
- Their structures were determined through comprehensive analysis of spectrometric data (e.g., NMR, MS) and confirmed via chemical transformations.
Impact:
- Expands the known diversity of furoquinoline alkaloids.
- Provides new chemical entities for potential pharmacological investigation and drug discovery efforts.
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