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Updated: May 5, 2026
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Intestinal lymphangiectasia associated with angiofollicular lymph node hyperplasia (Castleman's disease)
S F Moss1, D M Thomas, C Mulnier
1Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Abstract:
A patient presenting with predominantly gastrointestinal symptoms and a history of myocardial infarction was found to have ascites, hepatosplenomegaly, para-aortic lymphadenopathy, thrombocytosis, and a paraproteinaemia. A jejunal biopsy specimen showed lymphangiectasia and histology of the spleen and lymph nodes showed angiofollicular hyperplasia or Castleman's disease of the hyaline vascular type. This association has not previously been described and, moreover, systemic symptoms are unusual in this variant of Castleman's disease.
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