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Updated: Jul 15, 2026
Inguinal Subcutaneous White Adipose Tissue (ISWAT) Transplantation Model of Murine Islets
Published on: February 16, 2020
[Current status of islet transplantation]
José María Balibrea del Castillo1, Elena Vara Ameigeiras, Javier Arias-Díaz
1Departamento de Cirugía, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España. jose_balibrea@yahoo.es
Due to the numerous advances in islet transplantation in the last few years, clinical outcomes following this procedure are continually improving. Novel immunosuppression protocols, improved donor and recipient selection, and careful attention to the process of organ extraction, preservation and islet isolation have contributed to long-term success. The present article reviews the results of clinical islet transplantation and their relationship with the different advances introduced. The use of new islet sources such as living and non-heart-beating donors, as well as recent advances in our knowledge of the mechanisms of rejection and its prevention, are also reviewed.
Due to the numerous advances in islet transplantation in the last few years, clinical outcomes following this procedure are continually improving. Novel immunosuppression protocols, improved donor and recipient selection, and careful attention to the process of organ extraction, preservation and islet isolation have contributed to long-term success. The present article reviews the results of clinical islet transplantation and their relationship with the different advances introduced. The use of new islet sources such as living and non-heart-beating donors, as well as recent advances in our knowledge of the mechanisms of rejection and its prevention, are also reviewed.
