Radiographic assessment of Gardner's syndrome

Area of Science:

• Dentistry
• Oncology
• Radiology

Background:

• Gardner's syndrome (GS) is a genetic disorder characterized by intestinal polyps and various tumors.
• Osteomas, benign bone tumors, are frequently observed in the maxillofacial region in GS patients.
• Early detection of osteomas can be crucial for diagnosing GS.

Observation:

• A 47-year-old male with a history of intestinal polyps presented with an epidermoid cyst.
• Radiological evaluation, including panoramic radiography and CT scans, revealed multiple osteomas and compound odontomas in the maxillofacial region.
• CT imaging demonstrated osteomas invading the mandibular canal, indicating aggressive behavior.

Findings:

• The patient was diagnosed with Gardner's syndrome based on clinical and radiological findings.
• Multiple osteomas and odontomas were identified in the mandible and other maxillofacial areas.
• Osteomas exhibited invasive behavior into the mandibular canal.

Implications:

• This case underscores the importance of maxillofacial osteomas as potential early indicators of Gardner's syndrome.
• Comprehensive radiological assessment is vital for identifying the extent of osteomas and associated pathologies in GS.
• Understanding the invasive potential of osteomas in GS can guide treatment and management strategies.