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Published on: June 18, 2021
Association of ambulatory blood pressure with ischemic brain injury
Gary L Schwartz1, Kent R Bailey, Thomas Mosley
1Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. gschwartz@mayo.edu
Abstract:
Cerebral white matter hyperintensities on brain MRI (leukoaraiosis) are associated with increased risk of stroke and dementia. To assess the relationships of blood pressure level and circadian pattern with leukoaraiosis, we obtained 24-hour ambulatory blood pressure recordings and brain magnetic resonance images in 343 white and 267 black adults who were members of sibships that had >or=2 siblings with essential hypertension. In multiple linear regression models, factors associated with greater leukoaraiosis in both racial groups included age (P
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