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MR imaging appearance of insulinoma in an infant
Chandan Jyoti Das1, Jyotindu Debnath, Arun Kumar Gupta
1Department of Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. dascj@yahoo.com
Insights
This case study highlights a rare childhood pancreatic tumor, insulinoma, in an infant. Early diagnosis and surgical removal of the insulinoma prevented serious neurological issues.
Area of Science:
- Pediatric Endocrinology
- Surgical Oncology
- Diagnostic Imaging
Background:
- Insulinoma, a rare pancreatic neoplasm, can present in childhood with significant risks.
- Early diagnosis is crucial to prevent severe neurological complications associated with hypoglycemia.
- This report details a specific pediatric case for clinical insight.
Observation:
- An infant presented with seizures and behavioral changes, indicative of potential hypoglycemia.
- Laboratory tests revealed critically low random blood glucose levels (40 mg/dl).
- Magnetic Resonance Imaging (MRI) identified a well-defined pancreatic mass.
Findings:
- The pancreatic mass was located at the junction of the head and body.
- Imaging characteristics included hypointensity on T1-weighted and hyperintensity on T2-weighted MRI sequences.
- Histopathological examination confirmed the diagnosis of insulinoma.
Implications:
- Successful surgical enucleation of the insulinoma was achieved.
- Prompt recognition and treatment of pediatric insulinoma are vital for favorable outcomes.
- This case underscores the importance of considering rare pancreatic tumors in infants presenting with neurological symptoms.
Abstract:
Insulinoma is a very rare pancreatic neoplasm of childhood. Early recognition of insulinoma is important to ensure proper surgical treatment and prevent serious adverse neurological consequences. We describe here a case of insulinoma in an infant who presented with seizures and abnormal behaviour. Random blood glucose was found to be abnormally low (40 mg/dl). MRI showed a well-encapsulated mass (hypointense on T1-weighted and hyperintense on T2-weighted images) at the junction of the head and body of the pancreas. The tumour was successfully enucleated. Histopathology confirmed the diagnosis of insulinoma.
