Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasma viscosity in inflammatory bowel disease.

A J Lobo1, S C Jones, L D Juby

  • 1Gastroenterology Unit, General Infirmary, Leeds.

Journal of Clinical Pathology
|January 1, 1992
PubMed
Summary

Plasma viscosity is elevated in active Crohn's disease but not sensitive enough to replace erythrocyte sedimentation rate for monitoring disease activity. This study assessed plasma viscosity in inflammatory bowel disease patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Total hip arthroplasty for femoral fractures other than capital physeal fractures in dogs: 14 cases (2012-2020).

The Journal of small animal practice·2024
Same author

A survey of patient informational preferences when choosing between medical and surgical therapy for ulcerative colitis: a sub-study from the DISCUSS project.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2023
Same author

Teriparatide-associated calciphylaxis: a case series.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
Same author

A systematic review and meta-analysis of outcomes after elective surgery for ulcerative colitis.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2020
Same author

Simple ostectomy to address quadriceps impingement caused by distal femoral malunion in four dogs.

The Journal of small animal practice·2020
Same author

The informational and decisional preferences of patients undergoing surgery for Crohn's anal fistula: a qualitative study.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2019

Area of Science:

  • Gastroenterology
  • Clinical Chemistry

Background:

  • Inflammatory bowel disease (IBD) encompasses Crohn's disease (CD) and ulcerative colitis (UC).
  • Assessing disease activity is crucial for effective management of IBD.
  • Plasma viscosity (PV) is a measure of blood's resistance to flow.

Purpose of the Study:

  • To evaluate the relationship between plasma viscosity and disease activity in patients with IBD.
  • To compare PV as a potential biomarker for disease activity in CD and UC.

Main Methods:

  • Patients with CD (n=60) and UC (n=71) were recruited.
  • Disease activity was defined using established criteria for CD and UC.
  • Blood samples were analyzed for PV, hemoglobin, white blood cell count, platelets, erythrocyte sedimentation rate (ESR), albumin, and C-reactive protein (CRP).

Main Results:

  • PV was significantly higher in patients with active CD compared to inactive CD or active UC.
  • In CD, PV correlated with ESR, CRP, and platelet count.
  • In UC, PV correlated only with CRP.
  • PV demonstrated low sensitivity in detecting active CD, with nearly half of active CD patients having PV within the normal range.

Conclusions:

  • Plasma viscosity is associated with disease activity in Crohn's disease.
  • PV is not sensitive enough to serve as a replacement for ESR in monitoring the acute phase response in CD.
  • Further research may explore PV's role in specific IBD contexts.

Related Experiment Videos