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Updated: Jul 15, 2026

Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
Published on: October 10, 2020
Glutathione and associated enzymes in toxic cataractogenesis-selenite model
Joe Prasad Mathew1, Priya Joseph, V C Thomas
1Department of Zoology, St. Berchmans' College, Changanacherry - 686 101, India. jopmat@rediffmail.com
Abstract:
Glutathione, gamma-glutamyl cysteine synthetase (gamma -GCS) and glutathione reductase (GSH-R) activity were determined biochemically in the lens during various stages after subcutaneous administration of sodium selenite in multiple low dosages and single high dosages. The GSH concentration and gamma-GCS and GSH-R activity declined progressively after the selenite administration. The changes observed were discussed in relation to the possible role of selenite interaction with GSH and the enzymes.
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