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Early and late term management in caustic ingestion in children: a 16-year experience
1I.U. Istanbul School of Medicine, Department of Pediatric Surgery, Istanbul, Turkey.
Insights
Early esophageal rest and supportive care after corrosive ingestion in children significantly improve outcomes and reduce stricture development. Prompt management is crucial for preventing serious complications and promoting recovery.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Surgery
- Toxicology
Background:
- Accidental corrosive ingestion is a common cause of esophageal strictures in children.
- Acute phase management critically influences the development of esophageal strictures.
- Effective treatment strategies during the acute phase are essential for preventing long-term complications.
Purpose of the Study:
- To present clinical experience in managing pediatric caustic ingestion, focusing on acute phase interventions.
- To compare outcomes of immediate versus delayed treatment for corrosive esophageal strictures.
- To evaluate the efficacy of esophageal rest and supportive care in preventing stricture formation.
Main Methods:
- Retrospective analysis of 296 children with caustic ingestion from 1990-2005.
- Study group comprised 91 patients with esophageal strictures requiring dilatation.
- Comparison of outcomes between patients treated immediately (Group A) and those treated later (Group B).
- Acute management included esophagoscopy, esophageal rest via nasogastric tube for severe lesions, IV fluids, antibiotics, steroids, and ranitidine.
Main Results:
- Higher response rates to dilatation treatment were observed in Group A (immediate treatment).
- Group B (delayed treatment) showed increased rates of esophageal perforation.
- Sixty percent of Group A patients recovered within the first year, compared to none in Group B.
Conclusions:
- Esophageal rest combined with supportive medical treatment in the acute phase is effective in preventing stricture development after caustic ingestion.
- Early intervention and management are critical for improving recovery rates and reducing complications in pediatric corrosive esophagitis.
- Delayed treatment is associated with poorer outcomes and higher complication rates, including perforation.
Abstract:
Accidental corrosive ingestion is one of the common problems causing serious esophageal strictures in children. The acute phase treatment has a great effect on stricture development. In this study we aim to present our experience in the management of caustic ingestion, particularly during the acute phase. From January 1990 to January 2005, 296 children were admitted to our clinic with caustic ingestion. Ninety-one patients who received dilatation treatment due to esophageal strictures constituted the present study group. Forty-three of them were admitted to our centre immediately after caustic ingestion (Group A) whereas 48 of them received some kind of treatment in other hospitals and were referred us with the diagnosis of stricture 6 to 12 weeks after ingestion (Group B). In the acute phase, the patients were given nothing orally until esophagoscopy was performed in the first 24-48 hours. The patients with grades 2b and 3 lesions underwent a week of esophageal rest by using a nasogastric tube. IV fluids and broad-spectrum antibiotics with a single-dose steroid were given. IV ranitidine was also added to the medical treatment. If there were stricture formations on barium meal after 3 weeks, these patients underwent esophageal dilatation programmes. The response rates to dilatation treatment were higher in group A. In addition, increased perforation rates were observed in group B. Sixty per cent of patients in group A but none of the patients in group B have recovered in the first year. In conclusion, after caustic ingestion, esophageal rest combined with supporting treatment seems to provide a good success rate with respect to prevention of stricture development and other troublesome complications.
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