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Clinical trials: the viewpoint of children

J Cherrill1, H Hudson, C Cocking

  • 1Academic Division of Child Health, University of Nottingham, Derbyshire Children's Hospital, Derby, UK.

Archives of Disease in Childhood
|April 5, 2007
PubMed

Insights

Children understand risks in pediatric clinical trials, especially concerning payment. This study explored young patients' perspectives on research participation.

Area of Science:

  • Pediatric Research
  • Clinical Trials
  • Child Health

Background:

  • Understanding children's perspectives on clinical trials is crucial for ethical research.
  • Paediatric medical clinics serve a population of young individuals who may be candidates for clinical trials.

Purpose of the Study:

  • To determine the views of children aged 8-16 years on participating in paediatric clinical trials.
  • To identify specific concerns and understandings children have regarding clinical trial participation.

Main Methods:

  • Semi-structured interviews were conducted with 30 children attending paediatric medical clinics.
  • Participants' ages ranged from 8 to 16 years.

Main Results:

  • Nineteen out of 30 children recognized potential risks associated with clinical trials.
  • All participating children acknowledged risks related to financial compensation or payment for participation.

Conclusions:

  • Children possess an awareness of risks in paediatric clinical trials.
  • Financial incentives are a prominent consideration for children when evaluating participation in clinical research.

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