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Updated: Jul 15, 2026
08:19
Isolation of Leukocytes from the Human Maternal-fetal Interface
Published on: May 21, 2015
Expression of adhesion molecules during normal pregnancy.
J Pafilis1, A Batistatou, A Iliopoulou
1Department of Obstetrics and Gynaecology, City Hospital, Birmingham, UK.
Cell and Tissue Research
|April 5, 2007
Summary
Adhesion molecules are crucial for reproductive events from fertilization to fetal development. Their roles in cell interactions impact implantation and pregnancy success.
Area of Science:
- Reproductive biology
- Developmental biology
- Cell biology
Background:
- Cell-cell and cell-extracellular matrix interactions are fundamental to development.
- Reproductive processes like fertilization, embryogenesis, implantation, and placentation involve complex cellular events.
Purpose of the Study:
- To review the literature on the role of adhesion molecules in reproduction.
- To understand how adhesion molecules influence key developmental stages and pregnancy.
Main Methods:
- Literature review of studies on adhesion molecules in fertilization, embryogenesis, and implantation.
- Medline searches to identify relevant research.
Main Results:
- Adhesion molecules are involved in fertilization, embryogenesis, implantation, and placentation.
- These molecules regulate critical cellular functions including migration, growth, survival, proliferation, angiogenesis, invasion, and metastasis.
Conclusions:
- Adhesion molecules are key regulators of reproductive success.
- Understanding their function is vital for comprehending normal fetal development and pregnancy.
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