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Updated: Jul 15, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[Metachronic testicular tumor secondary to invasive bladder carcinoma]
Francisco Javier Vicente Prados1, José Luís Rosales Leal, Beatriz Honrubia Vilchez
1Servicio de Urología del Hospital Universitario de Granada, España. fjvicente@fundacionhvn.org
Objective:
To report a rare case of testicular metastasis secondary to an infiltrative transitional cell carcinoma years after radical surgery.
Case Report:
71-year-old male patient with history of infiltrative bladder tumor, status post radical cystoprostatectomy with urethrectomy. Seven years after surgery he presents with pain and swelling in the right testicle. Inguinal orchyectomy was carried out with the pathologic diagnosis of testicular metastasis of a high-grade transitional cell carcinoma. We perform a bibliographic review.
Results:
The patient is disease-free twelve months after orchyectomy.
Conclusions:
Apart from leukemia and lymphoma, testicular metastases are extremely rare. The existence of testicular metastases means a metastatic dissemination to other organs, therefore chemotherapy could improve prognosis.

