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Related Experiment Video

Updated: Jul 15, 2026

Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

Published on: September 5, 2018

Time-resolved contrast-enhanced carotid imaging using undersampled projection reconstruction acquisition.

Jiang Du¹, Sean B Fain, Frank R Korosec

¹Department of Medical Physics and Radiology, University of Wisconsin, Madison, WI, USA. jiangdu@ucsd.edu

Journal of Magnetic Resonance Imaging : JMRI

|April 6, 2007

Summary

Nonuniform angular spacing in 3D hybrid undersampled projection reconstruction (PR) significantly suppresses artifacts in contrast-enhanced (CE) time-resolved carotid imaging, enabling high-resolution dynamic scans.

Related Experiment Videos

Last Updated: Jul 15, 2026

Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

Published on: September 5, 2018

Area of Science:

Medical imaging
Magnetic Resonance Imaging (MRI)
Vascular imaging

Background:

Contrast-enhanced magnetic resonance angiography (CE-MRA) is crucial for carotid artery assessment.
Undersampled projection reconstruction (PR) techniques offer faster imaging but can introduce artifacts.
Optimizing projection acquisition is key to improving image quality in time-resolved CE-MRA.

Purpose of the Study:

To evaluate the effectiveness of nonuniform angular spacing in 3D hybrid undersampled PR for time-resolved carotid imaging.
To assess the impact of this technique on contrast-enhanced (CE) carotid imaging quality.
To determine if this method can improve artifact suppression in dynamic carotid imaging.

Main Methods:

A time-resolved hybrid sequence combining in-plane undersampled PR and through-plane Cartesian slice encoding was used.
Nonuniform distribution of projection angles, with increased density along the superior-inferior (S/I) direction, was implemented.
Phantom and healthy volunteer studies (n=7) were conducted to validate the technique.

Main Results:

Nonuniform projection spacing significantly reduced undersampling streak artifacts, particularly in the S/I direction.
The hybrid PR sequence achieved high temporal resolution (2 seconds/frame) and spatial resolution (1.0 x 1.0 x 1.5 mm³).
Simultaneous high-resolution and high temporal resolution dynamic imaging of the carotid arteries was demonstrated.

Conclusions:

High-resolution dynamic imaging of the carotid arteries is achievable using hybrid undersampled PR acquisition.
Nonuniform distribution of projections effectively suppresses undersampling streak artifacts.
This technique enhances the utility of CE time-resolved carotid imaging.