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Related Experiment Videos

Nasofacial phycomycosis: persistence pays.

Mark Harold Moore1, Dan Murphy, Craig James

  • 1Royal Australasian College of Surgeons Specialist Surgical Project, East Timor. mhmoore@internode.net.au

The Journal of Craniofacial Surgery
|April 7, 2007
PubMed
Summary
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Nasofacial phycomycosis, a rare fungal infection, often affects impoverished regions. Multimodality treatment combining surgery and antifungal drugs, particularly Voriconazole, proved successful in a 6-year clinical observation.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Tropical Medicine

Background:

  • Nasofacial phycomycosis is a rare fungal infection caused by Conidiobolus.
  • It is predominantly observed in developing countries, often associated with poverty.

Observation:

  • A 6-year clinical observation of nasofacial phycomycosis was conducted by a visiting volunteer surgical team.
  • The study documented the natural history and progression of the condition.

Findings:

  • Multimodality treatment, integrating surgical intervention and antifungal drug therapy, led to successful outcomes.
  • The infection demonstrated particular sensitivity to the newer generation antifungal agent, Voriconazole.

Implications:

  • This study highlights the effectiveness of combined surgical and antifungal approaches for nasofacial phycomycosis.

Related Experiment Videos

  • The findings underscore the potential of Voriconazole in treating this rare fungal infection, offering hope for improved patient management in resource-limited settings.