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Updated: Jul 15, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
Published on: March 8, 2015
Brain stimulation for the treatment of psychiatric disorders
Mark S George1, Ziad Nahas, Jeffrey J Borckardt
1Brain Stimulation Laboratory and Mood Disorders Clinic, Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA. georgem@musc.edu
Purpose Of Review:
There has been a resurgence of interest in brain stimulation techniques as therapies for psychiatric disorders. Various names are used for this class of treatments: neuromodulation, somatic therapies, brain stimulation techniques. The methods in this class range from non-invasive (transcranial magnetic stimulation) to invasive brain surgery (deep brain stimulation).
Recent Findings:
Within the past year, the results of several large multicenter trials have been published, clearing the way for US Food and Drug Administration approval of vagus nerve stimulation for recurrent treatment-resistant depression and a pending consideration of approving transcranial magnetic stimulation for the treatment of depression.
Summary:
This article reviews the most important recent clinically relevant manuscripts in this rapidly expanding new field.
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