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Published on: December 15, 2023
Peculiarities of active avoidance conditioning in rats with various forms of inherited arterial hypertension
L V Loskutova1, A V Filatov, N I Dubrovia
1Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences. loskutova@iph.ma.nsc.ru
Abstract:
Peculiarities of active avoidance conditioning were studied in NISAG rats (hereditary stress-induced arterial hypertension) and spontaneously hypertensive SHR rats. Conditioning was successful in 90% normotensive Wistar rats and in only 9.1% NISAG rats. Hypertensive SHR rats were intermediate between Wistar and NISAG rats by their learning capacity (66.7%). Our results suggest that differences in learning capacity of hypertensive rats are determined by genetic characteristics of animal behavior and emotional state, rather than blood pressure elevation.
