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Updated: Jul 15, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Optical coherence tomography study of vitreoretinal interface in full thickness macular hole associated with optic
P G Theodossiadis1, V G Grigoropoulos, J Emfietzoglou
12nd Department of Ophthalmology, University of Athens, 23 Likiou Street, 10674 Athens, Greece. george@heliasnet.gr
Purpose:
To evaluate by optical coherence tomography (OCT) the vitreous involvement in full thickness macular hole associated with optic disk pit maculopathy.
Methods:
Two patients with optic disk pit maculopathy and full thickness macular hole underwent OCT for evaluation of vitreous involvement in the pathogenesis of the disease. Fluorescein angiography and fundus photographs were also performed.
Results:
OCT documented the presence of vitreous traction at the edge of the full thickness macular hole in the first case and on the elevated macula in the second case. Partial posterior vitreous detachment was also noticed.
Conclusions:
Previously unreported OCT findings such as vitreous traction at the edge of the macular hole and on the elevated macula were found. OCT provided evidence for vitreous participation in full thickness macular hole associated with optic disk pit maculopathy. OCT was also able to show that the full thickness macular hole and optic disk pit maculopathy were probably caused by similar vitreous tractional forces.
