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Updated: Jul 15, 2026

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
Primary cerebral gliosarcoma: a case presentation with review of the literature
E E Pakos1, A C Goussia, E J Pitouli
1Department of Radiation Therapy, University Hospital of Ioannina, School of Medicine, Ioannina, Greece.
Abstract:
In this presentation we describe a rare case of a 42- year-old female with a large right frontal gliosarcoma (GS) treated with gross total resection of the tumor and postoperative external radiotherapy. The patient did not respond to treatment and she died 3 months after the end of radio- therapy. We also present a review of the literature on epidemiology, pathogenesis, clinical presentation, diagnosis and treatment of this uncommon clinical entity.

