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Control systems for the electric heart.

R K White1, D B Olsen

  • 1Division of Artificial Organs, University of Utah, Salt Lake City 84103-1414.

Artificial Organs
|October 1, 1991
PubMed
Summary
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Predicting and controlling cardiac output (CO) in total artificial heart (TAH) recipients remains challenging. Current TAH systems struggle to integrate physiological data for optimal blood flow regulation, highlighting a need for improved control strategies.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Physiology
  • Medical Device Technology

Background:

  • Accurate prediction and control of cardiac output (CO) in total artificial heart (TAH) recipients have evolved significantly.
  • Early TAH models featured limited control and fixed pumping parameters.
  • Modern TAH systems require complex interactions between blood volume and electric pumps for organ perfusion.

Purpose of the Study:

  • To review the evolution of methods for predicting and controlling cardiac output in TAH recipients.
  • To identify the limitations of current TAH control strategies.
  • To highlight the lack of consensus on appropriate physiological parameters for TAH regulation.

Main Methods:

  • Review of historical and current methodologies for TAH control.

Related Experiment Videos

  • Analysis of electromechanical systems and their integration with physiological feedback.
  • Examination of attempts to link end-organ function to TAH control.

    • Main Results:

    • Past TAH models had minimal control mechanisms.
    • Current advanced TAH devices necessitate intricate communication for maintaining blood flow.
    • Attempts to quantify end-organ flow, metabolic changes, and oxygen delivery for TAH control have been unsuccessful.
    • Existing devices focus on predicting CO via preload and afterload monitoring.
    • No consensus exists on which in vivo physiological parameters should regulate TAH output.

    Conclusions:

    • The precise control of cardiac output in TAH recipients remains a significant clinical challenge.
    • Current TAH technologies face difficulties in integrating comprehensive physiological feedback for optimal regulation.
    • Further research is needed to establish consensus on physiological parameters for effective TAH control.