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Updated: Jul 15, 2026

Modeling Cataract Surgery in Mice
Published on: December 1, 2023
[A case report of a recurrence of Mooren's ulcer after cataract surgery]
C Schweitzer1, D Touboul, C Ghiringhelli
1Service d'ophtalmologie, Hôpital Pellegrin, CHU, Bordeaux.
Abstract:
We report the case of Mooren's ulcer recurrence after uncomplicated cataract surgery in a 61-year-old woman. This cataract developed because of repetitive inflammation of the anterior chamber and corticotherapy. Local and general corticotherapy with cyclosporin 2% drops was started in association with an anterior lamellar graft and a conjunctival recession due to a preperforation condition. Secondarily cyclophosphamide was necessary to control recurrence with a good anatomic result and an increase in visual acuity. The case updates physiopathologic and diagnostic data on this rare limbic autoimmune ulcerative disease. The diagnosis was made by histology and the dosage of specific autoantibodies against cornea. The prevention of recurrence after surgery requires a long clinical quiescent period, minimally invasive surgery long after inflammation has subsided, and a gradual tapering of corticotherapy over several weeks.

