Great toe-to-thumb microvascular transplantation
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Updated: Jul 15, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Charles K Lee1, Gregory M Buncke
1The Buncke Clinic, CPMC-Davies Campus, 45 Castro Street, STE. 140N, San Francisco, CA 94114, USA.
Abstract:
Great toe to thumb transplantation offers the ideal reconstruction because it replaces the absent thumb with nearly identical anatomy. Functional donor site morbidity is minimal as compared with the aesthetic one; however, in comparison to the hand, the functional and aesthetic gain is tremendous. Anatomic and operative details are discussed along with preoperative and postoperative management. Postoperative functional evaluation of the thumb and donor site is assessed. Forty years of experience with this composite tissue transplantation has proven its status as the gold standard for thumb reconstruction.

