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[Clinically manifest gastrointestinal bleeding in patients subject to coronary angiography]

V Kojecký1, Z Coufal

  • 1Interni klinika IPVZ, Krajská nemocnice T Bati, a.s., Zlín. kojecky@bnzlin.cz

Vnitrni Lekarstvi
|April 11, 2007
PubMed

Insights

Upper gastrointestinal bleeding after coronary angiography is uncommon but carries a high mortality risk. Duodenal peptic lesions, often linked to aspirin use, are the most common cause.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Clinical Medicine

Background:

  • Coronary angiography is a common procedure for diagnosing heart conditions.
  • Upper gastrointestinal bleeding is a potential complication of medical treatments and procedures.

Purpose of the Study:

  • To determine the incidence and sources of acute upper gastrointestinal bleeding following coronary angiography.
  • To identify risk factors associated with this complication.

Main Methods:

  • A cohort of 5,955 patients undergoing coronary angiography were evaluated.
  • Gastroscopy was used to identify sources of bleeding in affected patients and assess pathologies in a control group.

Main Results:

  • Nine patients (0.15%) experienced upper gastrointestinal bleeding within days of angiography, with a 33% mortality rate.
  • Duodenal peptic lesions were the most frequent source of bleeding (44%).
  • Patients with bleeding were significantly older; regular acetylsalicylic acid use was associated with a higher incidence of ulcers.

Conclusions:

  • Acute upper gastrointestinal bleeding is a rare but serious complication of coronary angiography.
  • Duodenal peptic lesions, potentially exacerbated by acetylsalicylic acid, are the primary cause of bleeding.
  • The high mortality rate underscores the need for vigilance and prompt management.
Abstract

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