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Accurate visual guidance despite severe neglect.

Elizabeth J Wilkinson1, Jonathan L Richardson, Helen Sherk

  • 1Department of Biological Structure, University of Washington, Box 35-7420, Seattle, Washington 98195, USA. wilkie@u.washington.edu

The European Journal of Neuroscience
|April 11, 2007
PubMed
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In cats, inactivating the superior colliculus caused visual neglect. Surprisingly, cats still accurately guided foot placement to avoid obstacles in their neglected visual field, suggesting unconscious processing.

Area of Science:

  • Neuroscience
  • Vision Science
  • Animal Behavior

Background:

  • Unilateral superior colliculus inactivation induces profound visual neglect in cats.
  • Previous studies focused on neglect in gaze orientation and stimulus detection tasks.
  • The effect of neglect on visually guided motor behaviors like foot placement remained unexplored.

Purpose of the Study:

  • To investigate the impact of superior colliculus-induced neglect on visually guided foot placement during locomotion.
  • To determine if cats can process neglected visual stimuli for motor control despite conscious unawareness.

Main Methods:

  • Muscimol injections were used to unilaterally inactivate the superior colliculus in cats.
  • Perimetry was employed to assess the extent of the induced visual neglect.

Related Experiment Videos

  • Cats were tested on their ability to navigate a cluttered alley, requiring accurate foot placement.

    • Main Results:

    • Cats exhibited significant gaze deviation towards the inactivated side, rendering the ipsilesional visual field neglected.
    • Despite neglect, cats successfully and accurately avoided stepping on numerous scattered objects in their path.
    • Locomotion and obstacle avoidance were maintained even when visual stimuli were in the neglected hemifield.

    Conclusions:

    • Superior colliculus inactivation leads to neglect but does not abolish visually guided foot placement.
    • Cats demonstrate the capacity to utilize visual information from a neglected hemifield for precise motor actions.
    • This suggests a dissociation between conscious visual perception and subconscious visual processing for guiding behavior.