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Published on: February 9, 2011
Lung abscess in children
Patrick Patradoon-Ho1, Dominic A Fitzgerald
1Fairfield Hospital, Sydney, NSW, Australia.
Insights
Pediatric lung abscesses are rare but treatable. Interventional radiology with pigtail catheters offers faster symptom relief and shorter hospital stays compared to traditional antibiotics.
Area of Science:
- Pediatric Pulmonology
- Infectious Diseases
- Interventional Radiology
Background:
- Lung abscess is an infrequent pediatric condition with limited research.
- Historically managed with prolonged intravenous antibiotics.
Observation:
- Interventional radiology, utilizing percutaneous pigtail catheters under imaging guidance, is now a primary treatment.
- Improved diagnostics, including polymerase chain reaction, enhance pathogen identification from abscess fluid.
Findings:
- Pigtail catheter drainage may lead to quicker fever resolution, reduced antibiotic duration, and shorter hospitalizations.
- Common pathogens include Streptococcus species, Staphylococcus aureus, and Klebsiella pneumoniae.
- Culture results are crucial for guiding treatment, particularly in immunocompromised children.
Implications:
- Percutaneous drainage represents a significant advancement in managing pediatric lung abscesses.
- Early diagnosis and targeted antimicrobial therapy, guided by microbiology, are key.
- Children generally have a better prognosis for lung abscess than adults.
Abstract:
Lung abscess is an uncommon paediatric problem, with a paucity of quality data on the subject in the medical literature. Although the condition has for many years been managed successfully with prolonged courses of intravenous antibiotics, the evolution of interventional radiology has seen the use of percutaneously placed 'pigtail catheters' inserted under ultrasound and computed tomography guidance become the mainstay of therapy where such resources are available. This has been suggested to result in a more rapid defervescence of fever and symptoms, shorter periods of intravenous antibiotics and a decreased length of inpatient care. More invasive procedures, aspiration and drainage, together with improved microbiological diagnostic techniques, including polymerase chain reaction testing, has increased the yield of pathogens identified from abscess fluid samples. Culture results will guide treatment, especially for immunocompromised subjects who may develop a lung abscess as a complication of their underlying condition. The predominant pathogens isolated from primary lung abscesses in children include streptococcal species, Staphylococcus aureus and Klebsiella pneumoniae. Children with a lung abscess, both primary and secondary, have a significantly better prognosis than adults with the same condition.
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