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Updated: Jul 15, 2026

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens
08:23

Culture Methods to Determine the Limit of Detection and Survival in Transport Media of Campylobacter Jejuni in Human Fecal Specimens

Published on: March 10, 2020

Re-analysis of the risks attributed to ciprofloxacin-resistant Campylobacter jejuni infections

Trudy M Wassenaar1, Manfred Kist, Anno de Jong

  • 1Molecular Microbiology and Genomics Consultants, Tannenstrasse 7, 55576 Zotzenheim, Germany. mmgc.de@t-online.de

International Journal of Antimicrobial Agents
|April 11, 2007
PubMed

Insights

Fluoroquinolone-resistant Campylobacter infections do not cause more severe disease than susceptible infections. Foreign travel may prolong symptoms for both types of Campylobacter infections, but does not increase hospitalization.

Area of Science:

  • Infectious Diseases
  • Antimicrobial Resistance
  • Public Health

Background:

  • Campylobacter infections are a common cause of bacterial gastroenteritis.
  • The rise of fluoroquinolone resistance in Campylobacter poses a public health concern.
  • Previous studies have suggested fluoroquinolone-resistant Campylobacter may cause more severe illness.

Purpose of the Study:

  • To evaluate whether fluoroquinolone-resistant Campylobacter infections lead to more severe disease compared to susceptible infections.
  • To analyze the impact of foreign travel on Campylobacter infection severity.

Main Methods:

  • Comparative analysis of recent publications and novel surveillance data.
  • Statistical analysis of disease duration, hospitalization likelihood, and duration.
  • Inclusion of a large dataset comprising nearly 11,000 Campylobacter cases.

Main Results:

  • No significant difference in disease duration was found between fluoroquinolone-resistant and susceptible Campylobacter infections.
  • Campylobacter infections acquired during foreign travel showed a 1-2 day prolongation of symptoms for both resistant and susceptible cases.
  • Hospitalization likelihood and duration were not significantly increased for cases associated with foreign travel.

Conclusions:

  • Fluoroquinolone resistance in Campylobacter does not appear to increase disease severity.
  • Foreign travel is associated with prolonged symptoms but not increased hospitalization for Campylobacter infections.
  • Surveillance data and publication analysis confirm the lack of increased severity in resistant Campylobacter infections.

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