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Updated: Jul 15, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Brugada syndrome masquerading as febrile seizures
Jonathan Robert Skinner1, Seo-Kyung Chung, Carey-Anne Nel
1Greenlane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Grafton, Auckland, New Zealand. jskinner@adhb.govt.nz
Abstract:
Fever can precipitate ventricular tachycardia in adults with Brugada syndrome, but such a link has not been reported in children. A 21-month-old white girl presented repeatedly with decreased conscious level and seizures during fever. During a typical episode, rapid ventricular tachycardia was documented. The resting 12-lead electrocardiogram revealed a Brugada electrocardiogram signature. Resting electrocardiograms of the asymptomatic brother and mother were normal, but fever in the mother and pharmacologic stress with ajmaline in the brother revealed Brugada electrocardiogram features. Genetic testing revealed an SCN5A mutation in the affected family members.
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