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Dengue-associated maculopathy.

Kristine Enrile Bacsal1, Soon-Phaik Chee, Ching-Li Cheng

  • 1Department of Ocular Inflammation and Immunology, Singapore National Eye Centre.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|April 11, 2007
PubMed
Summary
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Dengue maculopathy presents with varied fundus changes, including hemorrhages and leakage. Early diagnosis using imaging techniques aids in visual recovery.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Dengue fever can cause ocular complications, including maculopathy.
  • Understanding the spectrum of dengue-associated maculopathy is crucial for timely diagnosis and management.

Observation:

  • A study reviewed 41 patients with dengue maculopathy over four years.
  • Seventy-one eyes exhibited maculopathy, with a mean visual acuity of 20/40.
  • Common findings included intraretinal hemorrhages, venular occlusion, and subretinal yellow dots.

Findings:

  • Fundus fluorescein angiography revealed venular occlusion (25%) and leakage (3-13%).
  • Indocyanine green angiography showed hypofluorescent spots in 50% of eyes with subretinal dots.
  • Visual field testing identified central or paracentral scotomas in 63% of affected eyes.

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Implications:

  • Imaging modalities like fundus fluorescein angiography, indocyanine green angiography, and optical coherence tomography are vital for diagnosing dengue maculopathy.
  • Steroid treatment led to significant visual acuity improvement in affected patients.
  • Early detection and management of dengue maculopathy can improve visual outcomes.