Related Experiment Video
Updated: Jul 15, 2026

New Framework for Understanding Cross-Brain Coherence in Functional Near-Infrared Spectroscopy (fNIRS) Hyperscanning Studies
Published on: October 6, 2023
Influence of bromazepam on cortical interhemispheric coherence
Isabel Sampaio1, Fernanda Puga, Heloisa Veiga
1Laboratório de Mapeamento Cerebral e Integração Sensório-Motora, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Avenida Venceslau Brás 71/Fundos, 22290-140 Rio de Janeiro, RJ, Brazil. belsampaio@gmail.com
Bromazepam, a common benzodiazepine, was studied for its effects on brain activity. This research found that bromazepam significantly enhances cortical interhemispheric coherence in healthy subjects.
Area of Science:
- Neuroscience
- Pharmacology
- Psychiatry
Background:
- Benzodiazepines are widely prescribed for anxiety and sleep disorders.
- Their impact on electroencephalographic (EEG) activity is not well-documented.
- Bromazepam is a commonly used benzodiazepine.
Purpose of the Study:
- To investigate the modulatory effects of bromazepam on brain dynamics.
- To analyze the impact of bromazepam on EEG coherence.
Main Methods:
- A double-blind experiment was conducted.
- Ten healthy subjects (5 male, 5 female) participated.
- EEG recordings were analyzed under bromazepam and placebo conditions.
Main Results:
- Bromazepam (3mg) significantly increased cortical interhemispheric coherence.
- EEG coherence was measured across three conditions: bromazepam, placebo 1, and placebo 2.
Conclusions:
- Bromazepam administration leads to increased interhemispheric coherence.
- This finding sheds light on the neurophysiological effects of bromazepam.
More Related Videos
08:25Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans
Published on: May 19, 2016
09:26Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Related Concept Videos
Sedatives and Hypnotics Drugs: Benzodiazepines
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
Anxiolytic Drugs: Benzodiazepines and Buspirone
Cerebral Hemispheres
CNS Depressants: Barbiturates and Benzodiazepines