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Related Experiment Video

Updated: Jul 15, 2026

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle

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Acute anaplasmosis in imported cattle.

A Bundza, B S Samagh

The Canadian Veterinary Journal = La Revue Veterinaire Canadienne

|November 1, 1982

Summary

Acute hemolytic anemia in imported Hereford cattle was caused by Anaplasma marginale infection. The study documented severe clinical signs, mortality, and diagnostic findings in affected animals.

Area of Science:

Veterinary Medicine
Parasitology
Animal Health

Background:

Anaplasma marginale is an intraerythrocytic rickettsial parasite causing significant economic losses in cattle.
Imported livestock can introduce infectious diseases to naive populations, posing a biosecurity risk.

Purpose of the Study:

To investigate the cause of acute hemolytic anemia in imported Hereford cattle in Quebec.
To identify the causative agent and document its pathological effects and diagnostic findings.

Main Methods:

Clinical examination of affected cattle.
Light and electron microscopy for Anaplasma marginale identification in erythrocytes.
Complement fixation test for serological diagnosis of anaplasmosis.

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Main Results:

Five of 18 imported Hereford cattle died from acute hemolytic anemia, icterus, and anorexia.
Anaplasma marginale was identified in erythrocytes of sick cattle using microscopy.
Complement fixation test revealed titers up to 1:320 in infected animals.

Conclusions:

Anaplasma marginale infection was confirmed as the cause of severe illness and mortality in imported cattle.
Microscopic evidence suggested a novel mechanism for Anaplasma marginale egress from erythrocytes.
The findings highlight the importance of disease surveillance in imported livestock to prevent outbreaks.