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Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...
General Structure of a Vertebra01:30

General Structure of a Vertebra

A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous column.

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Related Experiment Video

Updated: Jul 15, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
06:11

Anterior Cervical Discectomy and Fusion in the Ovine Model

Published on: October 5, 2009

Cervical intervertebral disc protrusion in two horses.

R R Foss, R M Genetzky, E A Riedesel

    The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
    |June 1, 1983
    PubMed
    Summary

    Cervical intervertebral disc protrusion caused severe ataxia in two horses. Diagnosis was confirmed using metrizamide myelography and necropsy, revealing spinal cord compression and degeneration.

    Area of Science:

    • Veterinary Neurology
    • Equine Medicine
    • Comparative Pathology

    Background:

    • Equine ataxia can stem from various neurological conditions affecting the spinal cord.
    • Cervical spinal cord lesions are a common cause of ambulatory deficits in horses.
    • Intervertebral disc disease is recognized but less frequently diagnosed in horses compared to other species.

    Purpose of the Study:

    • To report on two cases of cervical intervertebral disc protrusion in horses presenting with ataxia.
    • To describe the clinical signs, diagnostic methods, and pathological findings associated with this condition.
    • To highlight the utility of metrizamide myelography in diagnosing spinal cord compression in horses.

    Main Methods:

    • Clinical examination of two horses with tetraparesis and proprioceptive deficits.

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    Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
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    Last Updated: Jul 15, 2026

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  • Cerebrospinal fluid analysis to rule out inflammation or infection.
  • Metrizamide myelography to visualize spinal cord compression in one horse.
  • Necropsy and histological examination of the spinal cord in the second horse.
  • Main Results:

    • Both horses exhibited severe ataxia, predominantly in the pelvic limbs, with proprioceptive deficits and spasticity.
    • Cerebrospinal fluid analysis yielded normal results in both cases.
    • Metrizamide myelography confirmed spinal cord compression at the second cervical intervertebral space in one horse.
    • Necropsy revealed intervertebral disc protrusion between cervical vertebrae 6 and 7 in the other horse.
    • Histopathology showed significant fiber degeneration and demyelination in the affected spinal cords.

    Conclusions:

    • Cervical intervertebral disc protrusion is a potential cause of severe ataxia in horses.
    • Metrizamide myelography is a valuable diagnostic tool for identifying spinal cord compression.
    • Histopathological findings confirm the degenerative nature of the spinal cord lesions secondary to disc protrusion.