Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Monensis toxicity in lambs.

J G Bourque, M Smart, G Wobeser

    The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
    |October 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Accidental overfeeding of monensin in lamb grower rations caused toxicosis in 15-20% of the flock. Clinical signs included feed refusal, recumbency, and stiff gaits, confirming monensin toxicosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Is famine exposure during developmental life in rural Bangladesh associated with a metabolic and epigenetic signature in young adulthood? A historical cohort study.

    BMJ open·2016
    Same author

    Renal coccidiosis in wild ducks in Saskatchewan.

    Journal of wildlife diseases·2013
    Same author

    Physical medicine in Britain.

    Archives of physical medicine and rehabilitation·2010
    Same author

    A Lecture ON THE X-RAY DIAGNOSIS OF RENAL CALCULUS: Delivered at the Sick Children's Hospital, Great Ormond Street.

    British medical journal·2010
    Same author

    PATHOLOGY AND TREATMENT OF SPRAINS.

    British medical journal·2010
    Same author

    Nova scotia fetal risk project.

    Canadian family physician Medecin de famille canadien·2010
    Same journal

    Ethylene glycol intoxication: Use of the lactate gap for diagnosis and to determine length of intermittent hemodialysis treatment.

    The Canadian veterinary journal = La revue veterinaire canadienne·2026
    Same journal

    Medical management of multifocal immune-mediated punctate keratitis in 3 dogs: A case series.

    The Canadian veterinary journal = La revue veterinaire canadienne·2026
    Same journal

    Apramycin resistance in bacteria isolated from animals: A systematic review and meta-analysis.

    The Canadian veterinary journal = La revue veterinaire canadienne·2026
    Same journal

    Diagnostic Ophthalmology.

    The Canadian veterinary journal = La revue veterinaire canadienne·2026
    Same journal

    Is there a difference between locum and employed veterinarians?

    The Canadian veterinary journal = La revue veterinaire canadienne·2026
    Same journal

    Veterinary medicine and One Health in the age of AI.

    The Canadian veterinary journal = La revue veterinaire canadienne·2026
    See all related articles

    Area of Science:

    • Veterinary Medicine
    • Animal Nutrition
    • Toxicology

    Background:

    • Monensin is a commonly used ionophore antibiotic in livestock feed.
    • Accidental overdosage can lead to adverse health effects in animals.
    • Understanding the clinical presentation of monensin toxicosis is crucial for early diagnosis and intervention.

    Purpose of the Study:

    • To document the clinical signs and outcomes of accidental monensin overdosage in feedlot lambs.
    • To confirm the diagnosis of monensin toxicosis through comprehensive evaluation.
    • To highlight the importance of accurate feed mixing and ration formulation.

    Main Methods:

    • A group of 100 purebred lambs was fed a grower ration containing ten times the recommended level of monensin.
    • Clinical observations were recorded, including feed refusal and specific neurological and ambulatory signs.

    Related Experiment Videos

  • Diagnostic methods included clinical examination, history review, laboratory analysis, necropsy, and feed analysis.

    • Main Results:

    • Feed refusal was the initial clinical sign observed.
    • Within 48 hours, 15-20% of lambs exhibited clinical signs including recumbency, inability to rise, stiff gaits, and toe-walking.
    • Feed analysis confirmed excessive monensin levels, supporting the diagnosis.

    Conclusions:

    • Accidental overfeeding of monensin can lead to significant clinical manifestations of toxicosis in lambs.
    • Prompt diagnosis relies on recognizing clinical signs and confirming excessive monensin levels in feed.
    • This case underscores the critical need for precise feed formulation to prevent ionophore toxicosis in livestock.